FOR US HEALTHCARE PROFESSIONALS ONLY
What to do if your patient misses a dose of INVEGA TRINZA®
Time since last injection1
- Early or late by 2 weeks: Patients may be given the injection ±2 weeks from their scheduled 3-month dose
- Longer than 3½ months, but less than 4 months: Previous dose should be administered as soon as possible, then continue with 3-month injections
- 4 months up to and including 9 months: Do not administer the next dose, instead use the reinitiation table below
- Longer than 9 months: Reinitiate treatment with INVEGA SUSTENNA® (paliperidone palmitate) per its Prescribing Information. INVEGA TRINZA® can be resumed after >4 monthly INVEGA SUSTENNA® treatments
Reinitiation regimen after missing 4 to 9 months of INVEGA TRINZA®
Missing antipsychotic doses should be avoided.1
Switching back to INVEGA SUSTENNA®, if needed.
When switching patients from INVEGA TRINZA® back to INVEGA SUSTENNA®, INVEGA SUSTENNA® should be administered at the time of the next INVEGA TRINZA® dose using the equivalent 3.5-fold lower dose, as shown in this table.1
INVEGA SUSTENNA® should then continue to be dosed at monthly intervals.1
Conversion from INVEGA TRINZA® to INVEGA SUSTENNA®
*The initiation dosing as described in the Prescribing Information for INVEGA SUSTENNA® is not required.
Switching to paliperidone extended-release tablets, if needed
When switching from INVEGA TRINZA® to paliperidone extended-release tablets, INVEGA® (paliperidone), the daily dose of paliperidone extended-release tablets should be started 3 months after the last INVEGA TRINZA® dose and administered over the next several months after the last INVEGA TRINZA® dose as shown in this table.1
Conversion from INVEGA TRINZA® to once-daily INVEGA®1
Reference: 1. INVEGA TRINZA® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.